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Background Inflammatory diets may influence risk of cardiovascular disease. Subsequent cardiovascular disease is also influenced by adverse pregnancy outcomes (APOs) such as preterm birth, small‐for‐gestational‐age birth, gestational diabetes, and hypertensive disorders of pregnancy. However, the associations between inflammatory diet, APOs, and cardiometabolic health remain unclear. Methods and Results We used data from the nuMoM2b (Nulliparous Pregnancy Outcomes Study Monitoring Mothers‐to‐Be) HHS (Heart Health Study) to assess the relationship between dietary quality and cardiometabolic health. We calculated Energy‐Adjusted Dietary Inflammatory Index scores representing the inflammatory burden in a person's diet. We used linear regression to determine the association between Energy‐Adjusted Dietary Inflammatory Index score and cardiometabolic outcomes. We performed stratified analyses for outcomes with a significant interaction between Energy‐Adjusted Dietary Inflammatory Index and APO. Data were available from 3249 participants at a median of 3.1 years after delivery. Higher Energy‐Adjusted Dietary Inflammatory Index scores were associated with higher body mass index (B=0.29 kg/m2 [95% CI, 0.16–0.42]), waist circumference (0.66 cm [95% CI, 0.39–0.93]), diastolic blood pressure (0.26 mm Hg [95% CI, 0.09–0.44]), mean arterial pressure (0.23 mm Hg [95% CI, 0.06–0.40]), triglycerides (2.11 mg/dL [95% CI, 1.05–3.18]), creatinine (2.78 mg/dL [95% CI, 1.13–4.44]), insulin (exp[B]=1.04 [95% CI, 1.03–1.05]) and C‐reactive protein (exp[B]=1.07 [95% CI, 1.04–1.10]), and lower high‐density lipoprotein cholesterol (−0.41 mg/dL [95% CI, −0.66 to −0.37]) (all P |
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