Epithelioid hemangioma in the oral mucosa: A case report

Autor: Henriques Aguida Cristina Gomes, Vidal Manuela Torres Andion, Gurgel Clarissa Araujo, Rocha Sanyra Lopes Dias, Carneiro Braulio Junior, Almeida de Azevedo Roberto, dos Santos Jean Nunes
Jazyk: English<br />Serbian
Rok vydání: 2016
Předmět:
Zdroj: Srpski Arhiv za Celokupno Lekarstvo, Vol 144, Iss 9-10, Pp 535-540 (2016)
Druh dokumentu: article
ISSN: 0370-8179
2406-0895
DOI: 10.2298/SARH1610535H
Popis: Introduction. Epithelioid hemangioma is an uncommon benign vasoproliferative neoplasm that usually manifests as multiple red nodules in middle-aged adults. Case Outline. A 52-year-old male patient presented with a one-year history of a nodular lesion in the left buccal mucosa measuring 3 cm. The clinical hypothesis was lipoma. An excisional biopsy revealed a circumscribed lesion composed of lobules of vessels with perceptible or poor lumina, associated with a prominent inflammatory infiltrate consisting of eosinophils, histiocytes and chronic inflammatory cells. The endothelial cells composing the lesion had an epithelioid morphology and contained abundant eosinophilic cytoplasm. Immunohistochemistry for CD34, factor VIII, collagen IV, alpha-smooth muscle actin, and mast cells, as well as histochemical staining with Weigert’s orcein were performed. Conclusion. Vascular proliferations of soft tissues are a diverse and morphologically complex group of lesions that are difficult to diagnose. This report presents a case of oral epithelioid hemangioma, highlighting relevant morphological and immunohistochemical features that could help distinguish this condition from other neoplasms.
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