Predicting the risk of sarcopenia in elderly patients with patellar fracture: development and assessment of a new predictive nomogram

Autor: Yi-sheng Chen, Yan-xian Cai, Xue-ran Kang, Zi-hui Zhou, Xin Qi, Chen-ting Ying, Yun-peng Zhang, Jie Tao
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: PeerJ, Vol 8, p e8793 (2020)
Druh dokumentu: article
ISSN: 2167-8359
DOI: 10.7717/peerj.8793
Popis: Purpose To develop a risk prediction model for postoperative sarcopenia in elderly patients with patellar fractures in China. Patients and methods We conducted a community survey of patients aged ≥55 years who underwent surgery for patellar fractures between January 2013 and October 2018, through telephone interviews, community visits, and outpatient follow-up. We established a predictive model for assessing the risk of sarcopenia after patellar fractures. We developed the prediction model by combining multivariate logistic regression analysis with the least absolute shrinkage model and selection operator regression (lasso analysis) as well as the Support Vector Machine (SVM) algorithm. The predictive quality and clinical utility of the predictive model were determined using C-index, calibration plots, and decision curve analysis. We also conducted internal sampling methods for qualitative assessment. Result We recruited 137 participants (53 male; mean age, 65.7 years). Various risk factors were assessed, and low body mass index and advanced age were identified as the most important risk factor (P
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