Hydrogel-based dressings in the treatment of partial thickness experimentally induced burn wounds in rats

Autor: Milton Junior Cândido Bernardes, Randys Caldeira Gonçalves, Carolyna de Sousa Carvalho, Luciana Martins Rosa, Amanda Peixoto Ferreira, Marielle Sousa Vilela, Marina Clare Vinaud, Hélio Galdino Junior, Ruy de Souza Lino Junior
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Acta Cirúrgica Brasileira, Vol 37, Iss 4 (2022)
Druh dokumentu: article
ISSN: 1678-2674
DOI: 10.1590/acb370401
Popis: ABSTRACT Purpose: To compare four commercially available hydrogel formulations in the healing of partial thickness burns experimentally induced in rats. Methods: Wistar rats were used, and after the burn wound induction they were divided into the following treatment groups: G1) NaCl 0.9%; G2) 1% silver sulfadiazine; G3) Debrigel™; G4) Safgel™; G5) Dersani™; G6) Solosite™. The animals were followed during seven, 14 and 30 days after the injury induction. Morphometric, macroscopic and microscopic evaluations were performed. Results: The treatment with Dersani™ induced better results during the inflammatory and proliferative phases of the healing process (p
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