Autor: |
Margaret Moores, Raed A. Joundi, Nishita Singh, Andrew M. Penn, Kristine Votova, Eric E. Smith, Shelagh B. Coutts |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 7 (2024) |
Druh dokumentu: |
article |
ISSN: |
2047-9980 |
DOI: |
10.1161/JAHA.123.033817 |
Popis: |
Background Magnetic resonance imaging infarct topography may assist with determining stroke etiology. The influence of diffusion‐weighted imaging (DWI)‐positive lesions on etiology determination in patients with transient ischemic attack or minor stroke is not well studied. Methods and Results We prospectively enrolled patients between 2010 and 2017 in 2 studies; participants with a final diagnosis of probable or definite transient ischemic attack or stroke were pooled for analysis. The primary outcome was the adjudicated ischemic etiology. We compared proportion of each etiology (cardioembolic, large‐vessel, small‐vessel disease, other) in patients who had DWI positivity compared with DWI negativity. We used logistic regression to determine the adjusted odds ratio (OR) for each etiology compared with undetermined by DWI positivity. The final analysis included 1498 patients: 832 (55.5%) were DWI‐positive. DWI‐positive patients were more likely to be diagnosed with small‐vessel disease (19.1% versus 5.3%) and less likely with undetermined etiology (36.9% versus 53.0%; P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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