High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping: FLOAT

Autor: Joseph Rufo, Peiran Zhang, Zeyu Wang, Yuyang Gu, Kaichun Yang, Joseph Rich, Chuyi Chen, Ruoyu Zhong, Ke Jin, Ye He, Jianping Xia, Ke Li, Jiarong Wu, Yingshi Ouyang, Yoel Sadovsky, Luke P. Lee, Tony Jun Huang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-11 (2024)
Druh dokumentu: article
ISSN: 2055-7434
DOI: 10.1038/s41378-023-00648-3
Popis: Abstract Extracellular vesicles (EVs) have been identified as promising biomarkers for the noninvasive diagnosis of various diseases. However, challenges in separating EVs from soluble proteins have resulted in variable EV recovery rates and low purities. Here, we report a high-yield ( > 90%) and rapid (
Databáze: Directory of Open Access Journals