| Autor: |
Hiroshi Kobe, Yuki Sato, Koichiro Ohmura, Shohei Fujita, Ryosuke Mochizuki, Keisuke Tomii |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Current Problems in Cancer: Case Reports, Vol 4, Iss , Pp 100120- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2666-6219 |
| DOI: |
10.1016/j.cpccr.2021.100120 |
| Popis: |
Pembrolizumab-induced hemophagocytic lymphohistiocytosis (HLH) has rarely been reported, and it has no established treatment. The case of a 52-year-old woman with refractory pembrolizumab-induced HLH is presented. Her stage IV squamous cell lung cancer was treated using carboplatin/nab paclitaxel and pembrolizumab. After two cycles of treatment, Stevens-Johnson syndrome developed, followed by HLH. The HLH was refractory and did not improve with high-dose corticosteroids and cyclosporine A, but it improved with the addition of mycophenolate mofetil. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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