Pictorial essay: Allergic bronchopulmonary aspergillosis

Autor: Ritesh Agarwal, Ajmal Khan, Mandeep Garg, Ashutosh N Aggarwal, Dheeraj Gupta
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Indian Journal of Radiology and Imaging, Vol 21, Iss 04, Pp 242-252 (2011)
Druh dokumentu: article
ISSN: 0971-3026
1998-3808
DOI: 10.4103/0971-3026.90680
Popis: Allergic bronchopulmonary aspergillosis (ABPA) is the best-known allergic manifestation of Aspergillus-related hypersensitivity pulmonary disorders. Most patients present with poorly controlled asthma, and the diagnosis can be made on the basis of a combination of clinical, immunological, and radiological findings. The chest radiographic findings are generally nonspecific, although the manifestations of mucoid impaction of the bronchi suggest a diagnosis of ABPA. High-resolution CT scan (HRCT) of the chest has replaced bronchography as the initial investigation of choice in ABPA. HRCT of the chest can be normal in almost one-third of the patients, and at this stage it is referred to as serologic ABPA (ABPA-S). The importance of central bronchiectasis (CB) as a specific finding in ABPA is debatable, as almost 40% of the lobes are involved by peripheral bronchiectasis. High-attenuation mucus (HAM), encountered in 20% of patients with ABPA, is pathognomonic of ABPA. ABPA should be classified based on the presence or absence of HAM as ABPA-S (mild), ABPA-CB (moderate), and ABPA-CB-HAM (severe), as this classification not only reflects immunological severity but also predicts the risk of recurrent relapses.
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