Autor: |
Alyssa Milano, Suad Kabbaha, Kristian Thorlund |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Human Nutrition & Metabolism, Vol 30, Iss , Pp 200175- (2022) |
Druh dokumentu: |
article |
ISSN: |
2666-1497 |
DOI: |
10.1016/j.hnm.2022.200175 |
Popis: |
Several clinical studies have attributed the Mediterranean diet (MedDiet) to desirable metabolic health outcomes, but literature is saturated with studies conducted in Mediterranean regions questioning the diets applicability in non-Mediterranean countries. This review aimed to determine the effectiveness of MedDiet compared to a low-fat diet (LF-Diet) on metabolic components in those with or at risk of developing Metabolic Syndrome (MetS) in non-Mediterranean countries. We searched Medline, Embase and Global Health for randomized controlled trials published until October 2022 and a clinical trial register for ongoing studies. We identified 13 published trials (n = 1921) and 2 ongoing trials that met inclusion criteria. Random effects meta-analysis, yielded a statistically significant reduction in total cholesterol (MD -7.97, 95%CI -14.82 to −1.11) and systolic blood pressure (MD -2.04 mg/dl, 95%CI -3.68 to −0.39). Small non-significant pooled mean difference (MD) was observed for seven other MetS risk factors (body weight, waist circumference, diastolic blood pressure, blood glucose, triglycerides, LDL and HDL-cholesterol). Further inquiry is required to enhance certainty in estimates before health care providers can make an informed decision about possible dietary changes in MetS management and comorbidity prevention. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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