| Autor: |
Wanna Cai, Shengmei Xu, Ting Ma, Xiaoqi Zhang, Bo Liu, Fangfang Xu |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Arabian Journal of Chemistry, Vol 14, Iss 8, Pp 103292- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1878-5352 |
| DOI: |
10.1016/j.arabjc.2021.103292 |
| Popis: |
Five novel triterpenoid saponins, hovenidulciosides C−G (1–5), and one known saponin hovenidulcioside A1 (6) were isolated from the seeds of Hovenia dulcis Thunb. The structures of 1–5 were determined through spectroscopic methods such as HR-ESI-MS, 2D-NMR (1H–1H COSY, HSQC, HMBC, ROESY and TOCSY), UV and IR and chemical methods. There were amino acetylated substituent in the sugar resident of hovenidulciosides F−G, which were firstly reported from this genus. Compound 1 supressed ARE-luciferase activity in MDA-MB-231 cells and inhibited the Nrf2 protein levels in A549 cells. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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