Quantitative evaluation of retinal and choroidal microcirculation in inactive ocular sarcoidosis
| Autor: | Kubra Ozdemir Yalcinsoy, Yasemin Ozdamar Erol, Gozde Hondur, Pinar Cakar Ozdal |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Indian Journal of Ophthalmology, Vol 71, Iss 10, Pp 3367-3374 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0301-4738 1998-3689 94714347 |
| DOI: | 10.4103/IJO.IJO_3262_22 |
| Popis: | Purpose: To evaluate retinal and choroidal alterations in eyes with inactive ocular sarcoidosis and to compare the findings with healthy controls. Methods: This cross-sectional study included 11 patients with inactive ocular sarcoidosis (study group) and 11 healthy individuals (control group). Retinal and choroidal vascular differences were evaluated using optical coherence tomography angiography (OCTA) and enhanced depth imaging–optical coherence tomography (EDI-OCT). Results: A total of 21 eyes of ocular sarcoidosis patients without active inflammation and 22 eyes of healthy controls were analyzed. The mean whole-image deep capillary plexus vessel density was significantly lower in the study group than in the control group (P = 0.03). The acircularity index values were significantly higher, and the foveal density-300 values were significantly lower in the study group than in the control group (P = 0.01, both). The flow areas of the choriocapillaris at 1-, 2-, and 3-mm radius areas were also significantly lower in the study group (all P < 0.01). The mean choroidal thickness (CT) was significantly lower in all regions between nasal and temporal at 3000 μm in the study group (all P < 0.05). The choroidal vascularity index (CVI) values were also significantly lower in the study group (P < 0.01). Conclusion: Ocular sarcoidosis was associated with a reduction in CT and the CVI with a decrease in retinal vessel density and choriocapillary flow parameters. The combination of OCTA and EDI-OCT imaging may be useful in monitoring ocular sarcoidosis eyes to detect alterations in the retinal and choroidal layers. |
| Databáze: | Directory of Open Access Journals |
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