The relationship between the use of GLP-1 receptor agonists and the incidence of respiratory illness: a meta-analysis of randomized controlled trials

Autor:	Meixin Yu, Ruxin Wang, Ling Pei, Xiaofang Zhang, Jinjing Wei, Yun Wen, Han Liu, Haowen Ye, Jinghao Wang, Lihong Wang
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	GLP-1RA Diabetes mellitus type 2 Respiratory illness Randomized controlled trial Meta-analysis Nutritional diseases. Deficiency diseases RC620-627
Zdroj:	Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-21 (2023)
Druh dokumentu:	article
ISSN:	1758-5996
DOI:	10.1186/s13098-023-01118-6
Popis:	Abstract Aim We aimed to assess the association between the use of Glucagon-like peptide-1 receptor agonists and the risk of 12 respiratory diseases in patients with type 2 diabetes, obesity, or overweight. Method The PubMed (MEDLINE), EMBASE, Cochrane Library, and ClinicalTrials.gov databases were searched from the establishment of the database to December 24, 2022. Dichotomous outcomes were analyzed using RR and 95% CI calculated from fixed-effects models. Results Twenty-eight RCTs were ultimately included for analysis, involving a total of 77,485 participants. Compared to controls, patients with GLP-1RAs have a 14% lower risk of respiratory disease (RR 0.86, 95% CI 0.81–0.93 p
Databáze:	Directory of Open Access Journals
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