Distribution of major toxins in Rhinella marina parotoid macroglands using Desorption-Electrospray-Ionization mass spectrometry imaging (DESI-MSI)

Autor: Pedro L. Mailho-Fontana, Andreia M. Porcari, Marcos N. Eberlin, Carlos Jared, Marta Maria Antoniazzi, Daniel C. Pimenta, Juliana M. Sciani
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Toxicon: X, Vol 6, Iss , Pp - (2020)
Druh dokumentu: article
ISSN: 2590-1710
DOI: 10.1016/j.toxcx.2020.100033
Popis: Amphibian cutaneous glands secrete toxins used in different vital functions including passive defense. Through Desorption Electrospray Ionization-Imaging we analyzed the distribution of the major toxins of the toad Rhinella marina parotoid macroglands. Alkaloids and steroids showed characteristic distribution and intensity within the glands and were also present at lower levels on the skin surface. A comprehensive overview of toxins distribution in toads’ skin might help to understand their full biological role within the amphibians.
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