| Autor: |
Wei Zhang, Guoyu Yin, Heping Zhao, Hanzhi Ling, Zhen Xie, Chipeng Xiao, Yan Chen, Yufan Lin, Tao Jiang, Shengwei Jin, Jianguang Wang, Xinyu Yang |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Cell Death and Disease, Vol 12, Iss 1, Pp 1-14 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-4889 |
| DOI: |
10.1038/s41419-021-03393-5 |
| Popis: |
Abstract In inflamed joints, enhanced hyaluronic acid (HA) degradation is closely related to the pathogenesis of rheumatoid arthritis (RA). KIAA1199 has been identified as a hyaladherin that mediates the intracellular degradation of HA, but its extracellular function remains unclear. In this study, we found that the serum and synovial levels of secreted KIAA1199 (sKIAA1199) and low-molecular-weight HA (LMW-HA, MW |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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