Low-risk prostate cancer: evaluation of quality of life after surgical treatment and during active observation

Autor: E. N. Gasanov, E. V. Shpot, A. A. Magomedov, D. V. Chinenov, A. V. Proskura, P. I. Golovnya, E. S. Kapralova, V. S. Tikhonova, L. M. Rapoport
Jazyk: ruština
Rok vydání: 2021
Předmět:
Zdroj: Андрология и генитальная хирургия, Vol 22, Iss 4, Pp 60-67 (2021)
Druh dokumentu: article
ISSN: 2070-9781
1726-9784
DOI: 10.17650/1726-9784-2021-22-4-60-67
Popis: The study objective is to improve results of treatment of patients with low-risk prostate cancer (PC).Materials and methods. In the study, comparative analysis of data from 84 patients with low-risk PC was performed: 40 patients were included in the active observation group (group 1) and 44 patients underwent radical prostatectomy (group 2). For evaluation of functional responses the following questionnaires were used: Short Form 36 Health Quality Survey (SF-36), International Index of Erectile Function (IIEF-5), International Prostate Symptom Score (IPSS), Expanded Prostate Cancer Index Composite (EPIC-26). For control of oncological results, tests for prostate-specific antigen, digital rectal examination, magnetic resonance imaging of the pelvic organs with intravenous contrast, and confirmation biopsy of the prostate were preformed.Results. Mean score for the SF-36 questionnaire in the group 1 (active observation) at the beginning of the study was 63.2 ± 11.5 for mental health (MH) and 57.1 ± 9.8 for physical health (PH), while in the group 2 MH score was 63.1± 6.8, PH score was 56.2 ± 8.6. However, 18 months later in the group 1 mean MH score increased to 68.2 ± 10.1, mean PH score to 62.4 ± 7.8; in the group 2 PH score increased insignificantly to 64.2 ± 7.4 and PH score decreased to 54.8 ± 5.4 (p
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