Comparative study of the association of Ketamine to Dexmedetomidine, Medetomidine or Xylazine in rabbits

Autor: Dayanne Anunciação Silva Dantas Lima, Almir Pereira de Souza, Olívia Maria Moreira Borges, Vanessa Lira de Santana, Ana Lucélia de Araújo, Lorena da Cruz Moreira de Figueirêdo, Pedro Izidro da Nóbrega Neto, Wagner Costa Lima
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Brazilian Journal of Veterinary Medicine, Vol 36, Iss 1, Pp 35-41 (2014)
Druh dokumentu: article
ISSN: 0100-2430
2527-2179
Popis: ABSTRACT. Lima D.A.S.D., Souza A.P., Borges O.M.M., Santana V.L., Araújo A.L., Figueirêdo L.C.M., Nóbrega Neto P.I. & Lima W.C. [Comparative study of the association of Ketamine to Dexmedetomidine, Medetomidine or Xylazine in rabbits.] Estudo comparativo da associação de Cetamina à Dexmedetomidina, Medetomidina ou Xilazina em coelhos. Revista Brasileira de Medicina Veterinária 36(1):35-41, 2014. Programa de Pós-Graduação em Medicina Veterinária, Centro de Saúde e Tecnologia Rural, Universidade Federal de Campina Grande, Av. Universitária, s/n, Patos, PB 58708-110, Brasil. E-mail: dayannevet@yahoo.com.br There are a variety of different anesthetic techniques that aim to overcome the various problems of anesthesia in rabbits, such as handling stress and apnea during induction with inhalational anesthetic agents, reducing the risks of the procedure. The objective of this study was to compare the anesthetic effects promoted by ketamine associated/mixed with three different agonists α2 -adrenergics in rabbits. Were used 6 healthy animals, (SRD) mixed breed, weighing 2.42+0.36 kg, submerged to treatments called GCX, GCD and GCM. The fixed-dose ketamine (15 mg/kg) combined with xylazine (10 mg/kg) was administered intramuscularly in the GCX, the dexmedetomidine (0.05 mg/ kg) in GCD and medetomidine (0.25 mg/kg) in the GCM. Were evaluated the heart rate (HR), respiratory rate (ƒ), rectal temperature (RT), oxyhemoglobin saturation (SpO2 ), mean arterial pressure (MAP), glucose (GLI), variables electrocardiography (Pms, PmV, PRms, QRSms, RmV, QTms, RRms), latency, able anesthetic and recovery period. The records of the variables were initiated before drug administration (basal) and every 5 minutes after taking them for 50 minutes. Data were subjected to ANOVA followed by the Tukey test (P
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