Endobronchial mucosal nodules and actinomycosis in a child with activated phosphatidylinositol 3-kinase delta syndrome (APDS)

Autor: Kwan Fung Lam, Shun Chan, Lok Sang Kam, Janette Kwok, Pamela Pui-Wah Lee, David Shu Yan Lam
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 45, Iss , Pp 101909- (2023)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2023.101909
Popis: In this report, we describe a case of a 5-year-old girl with poor growth and unresolving pneumonia. Bronchoscopy showed numerous endobronchial mucosal nodules, consisting of dense lymphoid infiltrates. Bacterial culture of the nodule biopsy suggested endobronchial actinomycosis. Genetic test confirmed the diagnosis of APDS.
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