pH Homeostasis Linked with Capacitance Relaxation Phenomena and Electrostrictive Energy in Cancer Cells
| Autor: | T. K. Basak, T. Ramanujam, J. C. Kavitha, Poonam Goyal, Deepali Garg, Arpita Gupta, Suman Halder |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Sensors & Transducers, Vol 109, Iss 10, Pp 147-153 (2009) |
| Druh dokumentu: | article |
| ISSN: | 2306-8515 1726-5479 |
| Popis: | The present paper describes the capacitance relaxation phenomenon linked with the metastasis of cancer cells (US Patent No. TK Basak 5691178, 1997).The capacitance relaxation phenomenon is so significant that it can be correlated with the pH homeostasis and the electrostrictive energy of the cancer cells. The electrostrictive phenomenon is due to the composite dielectric property of the cancer cell concomitant with the capacitance relaxation phenomena. It is to be noted that pH homeostats in cancer cells are directly linked with the gene homeostat in a novel way so far as dephosphorylation of the oncogenes is concerned. This phenomenon in respect of pH homeostasis has been correlated with capacitance relaxation phenomenon and electrostrictive energy during pH mediated signal transduction phase. For this correlation DTREG has been used for the implementation of Datamining. For this analysis the type of model used in datamining is single tree for which the input data comprises of target and predictor variables. From the datamining result it is possible to conclude that the pH range (acidic) for all types of cancer is not unique and as such cancer has distinct specificity in respect of pH homeostasis. |
| Databáze: | Directory of Open Access Journals |
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