| Autor: |
Eleanor Watson, Aileen Sherry, Neil F. Inglis, Alex Lainson, Dushyanth Jyothi, Raja Yaga, Erin Manson, Lisa Imrie, Paul Everest, David G.E. Smith |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
EuPA Open Proteomics, Vol 4, Iss C, Pp 184-194 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
2212-9685 |
| DOI: |
10.1016/j.euprot.2014.06.003 |
| Popis: |
Gram-negative bacterial outer membrane proteins play important roles in the interaction of bacteria with their environment including nutrient acquisition, adhesion and invasion, and antibiotic resistance. In this study we identified 47 proteins within the Sarkosyl-insoluble fraction of Campylobacter jejuni 81-176, using LC–ESI-MS/MS. Comparative analysis of outer membrane protein sequences was visualised to reveal protein distribution within a panel of Campylobacter spp., identifying several C. jejuni-specific proteins. Smith–Waterman analyses of C. jejuni homologues revealed high sequence conservation amongst a number of hypothetical proteins, sequence heterogeneity of other proteins and several proteins which are absent in a proportion of strains. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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