| Autor: |
I. Dorigatti, C. A. Donnelly, D. J. Laydon, R. Small, N. Jackson, L. Coudeville, N. M. Ferguson |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-06006-6 |
| Popis: |
Clinical trials for the CYD-TDV dengue vaccine showed that vaccine efficacy varies with prior dengue exposure, but baseline serostatus is only known for 12% of subjects. Here, Dorigatti et al. use machine learning to impute baseline serostatus and determine vaccine efficacy by baseline serostatus, age and dengue serotype. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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