Retinoblastoma-like tumor with brain metastasis in a border collie

Autor: F. Eser ÖZGENCİL, E. Esma ÇERKEZ, Ece YAZAN, Nihan DİKBAŞ TSATSARONIS, Özgecan KULEYİNOĞLU, Volkan ÇAĞLAR, Dilek ÖZDEMİR, A. Perran GÖKÇE, Aydın GÜREL, Onur ÜLGENALP
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Kafkas Universitesi Veteriner Fakültesi Dergisi, Vol 30, Iss 3, Pp 401-405 (2024)
Druh dokumentu: article
ISSN: 1309-2251
DOI: 10.9775/kvfd.2023.31363
Popis: In this report, we described the clinical, ultrasound, contrast-enhanced T2-weighted brain magnetic resonance imaging (MRI), and histopathological findings of a retinoblastoma-like tumor with brain metastasis in a 3-year-old male Border Collie. Ophthalmoscopic and ultrasonographic examination revealed leukocoria associated with a solid mass of retinal origin in the left eye. Simultaneous contrast-enhanced T2- weighted brain MRI evaluation revealed solid masses at three different locations: the first one at the levels of the suprasellar cistern, third ventricle and chiasma opticum; the second one in the medulla oblongata adjacent to the caudal cranial fossa; and the third one in the left intraocular region. Histopathological examination of the extracted mass in the globe revealed a retinoblastoma-like tumor. The patient died before receiving radiotherapy treatment. In conclusion: this report highlights the importance of early diagnosis through ophthalmoscopic and ultrasonographic examinations. Emphasizing the brain as a potential secondary metastatic site, the report underscores the critical need to create a window for timely radiotherapy. Furthermore, the recommendation is made to evaluate dogs with leukocoria during ophthalmoscopic examination for both retinoblastoma and potential brain metastasis.
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