| Autor: |
John B Holcomb, Tiziana Cena, David Lockey, Luca Montagnani, Simona Cavallo, Andrea Cortegiani, Lorenzo Gamberini, Carlo Coniglio, Marco Tartaglione, Valentina Chiarini, Cristian Lupi, Giovanni Gordini, Tobias Gauss, Aimone Giugni, Maria Teresa Strano, Luca Carenzo, Carlo Alberto Mazzoli, Silvia Cavagna, Davide Allegri, Giovanni Sbrana, Andrea Caglià, Jacopo Pernechele, Andrea Mina, Roberto Vacca, Roberto Gioachin, Valeria Bonato, Claudia Monge, Paolo Frisoni, Luca Nicora, Giovanna Zilio, Cristina Barbarino, Andrea Paoli, Giacomo Magagnotti, Andrea Spagna, Alberto Trincanato, Francesca Verginella, Marta Pescolderung, Stefania Armani, Adriano Valerio, Giulio Desiderio, Edoardo Picetti, Michela Ciminello, Christian Tosato, Yuri Ferrara, Stefano Barbadori, Silvia Pini, Andrea Vignali, Alberto Baratta, Davide Durì, Calogero Centonze, Matteo Ciccolini, Alessandra Spasiano, Tommaso Marzano, Guido Gambetti, Domenico Minniti, Michela Rauseo, Gilda Cinnella, Rosanna Vaschetto, Giacomo Iapichino, Fabio Genco, Antonio Iacono, Annalisa Deiana, Marco Vidili, Massimiliano Carta, Alessio Ficarella, Flavia Baccari |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
BMJ Open, Vol 12, Iss 5 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2022-062097 |
| Popis: |
Introduction Major haemorrhage after injury is the leading cause of preventable death for trauma patients. Recent advancements in trauma care suggest damage control resuscitation (DCR) should start in the prehospital phase following major trauma. In Italy, Helicopter Emergency Medical Services (HEMS) assist the most complex injuries and deliver the most advanced interventions including DCR. The effect size of DCR delivered prehospitally on survival remains however unclear.Methods and analysis This is an investigator-initiated, large, national, prospective, observational cohort study aiming to recruit >500 patients in haemorrhagic shock after major trauma. We aim at describing the current practice of hypotensive trauma management as well as propose the creation of a national registry of patients with haemorrhagic shock. Primary objective: the exploration of the effect size of the variation in clinical practice on the mortality of hypotensive trauma patients. The primary outcome measure will be 24 hours, 7-day and 30-day mortality. Secondary outcomes include: association of prehospital factors and survival from injury to hospital admission, hospital length of stay, prehospital and in-hospital complications, hospital outcomes; use of prehospital ultrasound; association of prehospital factors and volume of first 24-hours blood product administration and evaluation of the prevalence of use, appropriateness, haemodynamic, metabolic and effects on mortality of prehospital blood transfusions. Inclusion criteria: age >18 years, traumatic injury attended by a HEMS team including a physician, a systolic blood pressure |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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