Autor: |
Germana Bancone, Gornpan Gornsawun, Pimnara Peerawaranun, Penporn Penpitchaporn, Moo Kho Paw, Day Day Poe, December Win, Naw Cicelia, Mavuto Mukaka, Laypaw Archasuksan, Laurence Thielemans, Francois Nosten, Nicholas J White, Rose McGready, Verena I Carrara |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
PLOS Global Public Health, Vol 2, Iss 6, p e0000475 (2022) |
Druh dokumentu: |
article |
ISSN: |
2767-3375 |
DOI: |
10.1371/journal.pgph.0000475 |
Popis: |
Very high unconjugated bilirubin plasma concentrations in neonates (neonatal hyperbilirubinaemia; NH) may cause neurologic damage (kernicterus). Both increased red blood cell turn-over and immaturity of hepatic glucuronidation contribute to neonatal hyperbilirubinaemia. The incidence of NH requiring phototherapy during the first week of life on the Thailand-Myanmar border is high (approximately 25%). On the Thailand-Myanmar border we investigated the contribution of genetic risk factors to high bilirubin levels in the first month of life in 1596 neonates enrolled in a prospective observational birth cohort study. Lower gestational age ( |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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