Redox approaches derived Tin (Ⅳ) oxide nanoparticles/graphene nanocomposites as the near-infrared absorber for selective human prostate cancer cells destruction

Autor: Jin-Sheng Cheng, Qingqin Liang, Haixin Chang, Jingying Xu, Wenjuan Zhu
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Nano Biomedicine and Engineering, Vol 4, Iss 2, Pp 76-82 (2012)
Druh dokumentu: article
ISSN: 2150-5578
DOI: 10.5101/nbe.v4i2.p76-82
Popis: In this paper, Tin (Ⅳ) oxide nanoparticles/graphene (SnO2/GR) nanocomposites were prepared via vacuum thermo treatment of Tin (0) and graphene oxide (GO). A redox reaction would occur readily in this process, in which the novel oxygen donor: GO could act as the oxidizing agent to oxidize Tin (0) to Tin (Ⅳ), meanwhile, the graphene precursor: GO would be simultaneously reduced to graphene by Tin (0) readily. The resulted composites were characterized by Fourier transform infrared spectrometry, scanning electron microscopy, and X-ray diffraction spectroscopy ect.. The novel SnO2/GR nanocomposites could combine both advantages of inorganic metal nanoparticles and graphene for near infrared spectroscopy (NIR) light absorption to generate heat, which fosters SnO2/GR a special candidate for photothermal ablation therapy (PTA) with NIR. Further investigations show that the SnO2/GR nanocomposites with NIR features could provide viable option for enhancing the thermal deposition and specificity of hyperthermia treatments for elimination of human prostate cancer (PC3).
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