Investigation of serum level relationship of pro-inflammatory and anti-inflammatory cytokines with vitamin D among healthy Ghanaian population

Autor: Maxwell Hubert Antwi, Samuel Asamoah Sakyi, Seth Christopher Yaw Appiah, Tonnies Abeku Buckman, Joseph Yorke, Aaron Siaw Kwakye, Isaac Darban, Peter Agoba, Akwasi Minnah Addei
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Research Notes, Vol 17, Iss 1, Pp 1-8 (2024)
Druh dokumentu: article
ISSN: 1756-0500
DOI: 10.1186/s13104-024-06721-y
Popis: Abstract Background The interplay between vitamin D status and inflammatory cytokines in a supposedly sufficient sunshine environment has not well been evaluated. The study sought to determine their association. Methods This cross-sectional study involved 500 healthy adult blood donors from some selected hospitals in Ghana enrolled from June to November 2016. Venous blood samples were obtained from participants, 25(OH)D, TNF-alpha, IFN-gamma, and IL 10 were measured using enzyme linked immunosorbent assay (ELISA) technique. Serum levels of 25(OH)D
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