Autoimmune pulmonary alveolar proteinosis with features similar to nonspecific interstitial pneumonia

Autor: Koki Fujii, Hideyuki Takeshima, Taku Nishimura, Toshio Sakatani, Yoshio Masuda, Teppei Morikawa, Kazuhiro Usui
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Respiratory Medicine Case Reports, Vol 36, Iss , Pp 101591- (2022)
Druh dokumentu: article
ISSN: 2213-0071
DOI: 10.1016/j.rmcr.2022.101591
Popis: A 58-year-old woman with cough and dyspnea who was suspected of having idiopathic interstitial pneumonia had been treated with corticosteroids and cyclosporine, but the symptoms had worsened. There were no findings to suspect pulmonary alveolar proteinosis (PAP) in the bronchoalveolar lavage fluid, 17 months after the start of treatment. The transbronchial lung biopsy specimens showed eosinophilic bodies that strongly stained with periodic acid-Schiff staining. Anti-granulocyte macrophage colony-stimulating factor (anti-GM-CSF) antibodies were detected in her serum. We diagnosed the patient with autoimmune PAP. Thus, we present a rare case of PAP presenting atypical radiological images and bronchoalveolar lavage fluid findings.
Databáze: Directory of Open Access Journals