| Autor: |
Sepideh Kaviani, Kristine R. Polley, Michael K. Dowd, Jamie A. Cooper, Chad M. Paton |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of Functional Foods, Vol 87, Iss , Pp 104802- (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1756-4646 |
| DOI: |
10.1016/j.jff.2021.104802 |
| Popis: |
Angiopoietin-like proteins (ANGPTL) 3, -4 and -8 regulate lipid metabolism by altering lipoprotein lipase activity, but it is not known how cottonseed oil (CSO) differentially affects postprandial responses of ANGPTL’s in humans. We compared the effect of a diet rich in either CSO or olive oil (OO) on fasting and postprandial ANGPTL’s. Fifteen males completed two feeding trials in random order: 1) a CSO-rich diet and 2) an OO-rich diet with fasting and postprandial blood samples collected pre-diet at visit 1 (v1) followed by a 5-day feeding trial and a post-diet visit (v2) identical to v1 and a 2–4-week washout period. Fasting ANGPTL4 and ANGPTL8 decreased from v1 to v2 after the CSO diet and increased with the OO diet. Postprandial ANGPTL3, -4, and -8 were lower following the CSO meal. The lipid-lowering effects of CSO may be mediated by reduced fasting and postprandial ANGPTL3, -4 and -8 responses. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full Text from ScienceDirect