Antifatigue and Antioxidant Activity of Alcoholic Extract from Saussurea involucrata

Autor: Jang-Chang Lee, Jung-Yie Kao, Daih-Huang Kuo, Chien-Fu Liao, Chi-Hung Huang, Ling-Ling Fan, Tzong-Der Way
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Journal of Traditional and Complementary Medicine, Vol 1, Iss 1, Pp 64-68 (2011)
Druh dokumentu: article
ISSN: 2225-4110
DOI: 10.1016/S2225-4110(16)30058-X
Popis: Fatigue is a noticeable and highly prevalent symptom in tense, industriously, and economically affluent modern society. Therefore, new antifatigue agents to smooth the fatigue feature are an energetic topic. The total ethanol extract (ESI) of Saussurea involucrata Kar et Kir., known as Tian-Shan snow lotus, was evaluated for antifatigue activity in ICR mice with mice forced swimming test and the determination of the contents of blood lactic acid and serum urea nitrogen. ESI (0.05, 0.15, 0.25 g/kg) was administered orally to mice for 4 weeks. The average swimming times to exhaustion of the ESI-treated ICR mice (0.15, 0.25 g/kg) were prolonged by 132% and 180% (p
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