| Autor: |
Po-Lin Chen, Chi-Jung Wu, Pei-Jane Tsai, Hung-Jen Tang, Yin-Ching Chuang, Nan-Yao Lee, Ching-Chi Lee, Chia-Wen Li, Ming-Chi Li, Chi-Chung Chen, Hung-Wen Tsai, Chun-Chun Ou, Chang-Shi Chen, Wen-Chien Ko |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 9, Iss 11, p e111213 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0111213 |
| Popis: |
BACKGROUND: The objective of this study was to compare virulence among different Aeromonas species causing bloodstream infections. METHODOLOGY/PRINCIPAL FINDINGS: Nine of four species of Aeromonas blood isolates, including A. dhakensis, A. hydrophila, A. veronii and A. caviae were randomly selected for analysis. The species was identified by the DNA sequence matching of rpoD. Clinically, the patients with A. dhakensis bacteremia had a higher sepsis-related mortality rate than those with other species (37.5% vs. 0%, P = 0.028). Virulence of different Aeromonas species were tested in C. elegans, mouse fibroblast C2C12 cell line and BALB/c mice models. C. elegans fed with A. dhakensis and A. caviae had the lowest and highest survival rates compared with other species, respectively (all P values |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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