Development of muco-adhesive orally disintegrating tablets containing tamarind gum-coated tea powders for oral care

Autor: Rika Kiniwa, Masaki Miyake, Shin-ichiro Kimura, Shigeru Itai, Hiromu Kondo, Yasunori Iwao
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
Druh dokumentu: article
ISSN: 2590-1567
DOI: 10.1016/j.ijpx.2019.100012
Popis: The aim of this study was to design and evaluate muco-adhesive orally disintegrating tablets manufactured by microwave irradiation and containing polysaccharide. We prepared orally disintegrating tea tablets (ODTTs) containing a 1 w/w% mass fraction of one of five polysaccharides (gum arabic, carrageenan, guar gum, tamarind gum, or pectin) and evaluated the swelling degree, tablet hardness, friability, disintegration time, and adhesive properties. All tablets had a swelling degree of about 1 mm, a hardness of over 13 N, and a friability degree of
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