PATHOMORPHOLOGICAL CHANGES IN THE THYROID GLAND IN TOXIC DIFFUSE GOITER

Autor: S. KURBONOV, M.K. GULOV, I.A. DAVLATOV, E.H. TAGAYKULOV
Jazyk: English<br />Russian
Rok vydání: 2017
Předmět:
Zdroj: Паёми Сино, Vol 19, Iss 3, Pp 320-324 (2017)
Druh dokumentu: article
ISSN: 2074-0581
2959-6327
DOI: 10.25005/2074-0581-2017-19-3-320-324
Popis: Objective: To study the main pathomorphological and morphometric structural rearrangements of thyroid tissue (TT) formations in toxic diffuse goiter (TDG). Methods: By the methods of anatomical preparation and histological sections, macro and microscopic structural features of the thyroid gland were studied in 22 patients with TDG; both sexes aged 36 to 60 years, operated in the Department of General Surgery, State Clinical Hospital № 5, named by Academician K.T. Tadjiev Results: An analysis of the degree of progression of pathomorphological changes in the tissue and the follicular structure of the thyroid gland revealed a dependence on the duration and severity of the disease. The results of a quantitative study showed that the average diameter of the follicles, as compared with the norm (70.8±1.19 μm), became larger (80.8±1.26 μm). The height of the follicular epithelium for this pathology was 15.16±0.22 μm, with a norm of 10.06±0.09 μm (p
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