Racial and social-economic inequalities in systemic chemotherapy use among adult glioblastoma patients following surgery and radiotherapy

Autor:	Fei Xu, Xin Hua, Mengdi Wang, Weiguo Cao, Shubei Wang, Cheng Xu, Jiayi Chen, Yunsheng Gao, Linlin Chen, Weiqiong Ni
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Global health GBM Post-surgery Beam radiotherapy Systemic chemotherapy Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-68962-y
Popis:	Abstract Not all patients with glioblastoma multiforme (GBM) eligible for systemic chemotherapy after upfront surgery and radiotherapy finally receive it. The information on patients with GBM was retrieved from the surveillance, epidemiology, and end results database. Patients who underwent upfront surgery or biopsy and external beam radiotherapy between 2010 and 2019 were eligible for systemic chemotherapy. The available patient and tumor characteristics were assessed using multivariable logistic regression and chi-squared test. Out of the 16,682 patients eligible, 92.1% underwent systemic chemotherapy. The characteristics linked to the lowest systemic chemotherapy utilization included tumors of the brain stem/cerebellum (P = 0.01), former years of diagnosis (P = 0.001), ≥ 80 years of age (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1df52d4f5ce6416b854c2d28d63a39d2 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.