Slowly Growing Nodule on the Trunk: Cutaneous Granular Cell Tumor

Autor: Özge Gündüz, Gül Erkin, Banu Bilezikçi, Gökhan Adanalı
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Dermatopathology, Vol 3, Iss 2, Pp 23-27 (2016)
Druh dokumentu: article
ISSN: 2296-3529
00044547
DOI: 10.1159/000445479
Popis: Granular cell tumor (GCT) is a rare benign neoplasm of the skin that accounts for 0.5% of all soft-tissue tumors. The tumor mostly presents with a symptomatic slowly growing solitary nodule and overlying normal skin; therefore, it is not always considered in the differential diagnosis. Here, we report a 58-year-old female patient who presented with a 4-year history of a slowly growing mass, with a dimension of 5 × 4 cm on her left waist, diagnosed as a GCT at the histopathological examination. The neoplastic cells had centrally located nuclei and granular eosinophilic cytoplasm and stained positively for S100, neuron-specific enolase, and CD68 antibodies. Fifteen months after surgery, the patient still showed no signs of local recurrence or metastases. Although a large diameter is a feature of malignant GCT, our case with cutaneous GCT was localized on the trunk and did not present malignant features clinically and histopathologically.
Databáze: Directory of Open Access Journals
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