Radical Prostatectomy in High-Risk Prostate Cancer Patients: Results of a Single- Institution Study
| Autor: | Virote Chalieopanyarwong, Worapat Attawettayanon, Watid Kanchanawanichkul, Choosak Pripatnanont |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Journal of Health Science and Medical Research (JHSMR), Vol 36, Iss 1, Pp 45-51 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2586-9981 2630-0559 |
| Popis: | Objective: To evaluate long-term outcomes of radical prostatectomy and bilateral pelvic lymph node dissection (RP) for high-risk prostate cancer (PC). Material and Method: A retrospective review of high-risk PC patients who received RP, identified from medical records. We collected data from Songklanagarind Hospital, Prince of Songkla University from 2007 to 2015. The Kaplan-Meier method and Cox proportional regression models were used to analyze clinical recurrence (CR) and biochemical recurrence (BCR). Results: In 79 patients, the median follow-up was 27.2 months. The 3-year and 5-year biochemical free survival in men with high-risk PC were 67.7% and 62.9% respectively. Multivariate analysis shows that pathologic stage 3a (hazard ratio=4.87; 95% confidence interval=1.01-23.38) was independently associated with cancer control. Conclusion: Data support the belief that RP has a place in the treatment of high-risk PC. RP was a long-term cancer control in patients with high-risk PC. Only pathologic staging was independently associated with cancer control outcome. |
| Databáze: | Directory of Open Access Journals |
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