The impact of aspirin on Klebsiella pneumoniae liver abscess in diabetic patients

Autor: Chien-Hsiang Tai, Chien-Ning Hsu, Shih-Cheng Yang, Cheng-Kun Wu, Chih-Ming Liang, Wei-Chen Tai, Seng-Kee Chuah, Chen-Hsiang Lee
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-020-78442-8
Popis: Abstract In this study, we aimed to investigate the impact of aspirin on the risk of pyogenic liver abscess caused by Klebsiella pneumoniae (KP-PLA) and invasive KP-PLA syndrome (IKPS) in diabetic patients. Diabetic patients who were propensity-score matched were retrospectively included from hospital-based database. Kaplan–Meier approach with a log-rank test was used to compare the cumulative incidences of KP-PLA including IKPS between aspirin users and non-users. Totally, 63,500 patients were analyzed after propensity-score matching (1:1). Compared with that of non-users, the incidence of KP-PLA was significantly reduced in aspirin users (0.31% vs. 0.50%, p
Databáze: Directory of Open Access Journals
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