Prospective, historically controlled study to evaluate the efficacy and safety of a new paediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO).

Autor:	Jaime Altcheh, Luis Castro, Juan C Dib, Ulrike Grossmann, Erya Huang, Guillermo Moscatelli, Jimy José Pinto Rocha, Teresa Estela Ramírez, CHICO Study Group
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270
Zdroj:	PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008912 (2021)
Druh dokumentu:	article
ISSN:	1935-2727 1935-2735
DOI:	10.1371/journal.pntd.0008912
Popis:	Nifurtimox is a recommended treatment for Chagas disease, but data from treated children are limited. We investigated the efficacy, safety and tolerability of nifurtimox administered as divisible, dispersible 30 mg and 120 mg tablets in children with Chagas disease. In this blinded, controlled study conducted January 2016-July 2018, 330 patients aged
Databáze:	Directory of Open Access Journals
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