Membrane association and remodeling by intraflagellar transport protein IFT172

Autor: Qianmin Wang, Michael Taschner, Kristina A. Ganzinger, Charlotte Kelley, Alethia Villasenor, Michael Heymann, Petra Schwille, Esben Lorentzen, Naoko Mizuno
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-07037-9
Popis: Cilia formation requires Intraflagellar transport (IFT) to move ciliary building blocks and signaling components into the cilium. Here authors use in vitro reconstitution and electron microscopy on IFT172 and reveal its ability to remodel large membrane surfaces into small vesicles.
Databáze: Directory of Open Access Journals