Pleural manometry during thoracocentesis in patients with malignant pleural effusion: A randomized controlled trial

Autor: Aly Sherif Hassaballa, Ahmed Mostafa, Tamer Hikal, Ahmed Elnori, Hany Hasan Elsayed
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Canadian Journal of Respiratory Therapy, Vol 59, Pp 33-44 (2023)
Druh dokumentu: article
ISSN: 2368-6820
DOI: 10.29390/cjrt-2022-047
Popis: Background: Large-volume therapeutic thoracocentesis may be associated with pulmonary congestion or a more serious complication; re-expansion pulmonary edema (RPE). We investigated whether monitoring pleural pressure with manometry during thoracocentesis would prevent these pulmonary symptoms/RPE and allow larger volume drainage. Methods: We did a randomized controlled trial involving 110 patients with large malignant pleural effusions. Patients were randomly allocated to obtain thoracocentesis with or without pleural manometry. We measured the incidence of pulmonary congestion symptoms, total fluid aspirated, and pleural pressures in both groups. This trial is listed on ClinicalTrials.gov as NCT04420663. Results: The mean amount of total thoracocentesis fluid withdrawn from the control group was 945.4±78.9 (mL) and 1690.9±681.0 (mL) from the intervention group (P
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