Inflammatory reaction in experimental non-coronary metabolic myocardial infarction
| Autor: | L. D. Khidirova, L. V. Vokhmintseva, N. N. Mayanskaya, S. D. Mayanskaya, V. I. Sharapov |
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| Jazyk: | ruština |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Кардиоваскулярная терапия и профилактика, Vol 9, Iss 1, Pp 74-78 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1728-8800 2619-0125 |
| Popis: | Aim. To study inflammatory reaction specifics in Vistar rats with non-coronary metabolic myocardial infarction (MMI). Material and methods. Electrocardiographical and histological verification of MMI. Measurement of neutrophil biocide activity, antioxidant system activity, the levels of lipid peroxidation (LP) products and pro-inflammatory cytokines, and plasma lipoprotein (LP) profile assessment. Results. In MMI rats, neutrophil biocide activity was increased, the balance between pro- and antioxidant systems was disturbed, plasma LP profile was affected, with increased pro-inflammatory LP levels, and pro-inflammatory cytokine concentrations were elevated. Conclusion. The observed inflammatory reaction specifics determined the clinical course of MMI. |
| Databáze: | Directory of Open Access Journals |
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