Effects of Portulaca oleracea ethanolic extract on reproductive system of aging female mice
| Autor: | Akram Ahangarpour, Zohreh Lamoochi, Hadi Fathi Moghaddam, Seyed Mohamad Taghi Mansouri |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Iranian Journal of Reproductive Medicine, Vol 14, Iss 3, Pp 205-212 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1680-6433 2008-2177 |
| Popis: | Background: Aging contains morphological and functional deterioration in biological systems. D-galactose (D-gal) generates free radicals and accelerates aging. Portulaca oleracea (Purslane) may have protective effect against oxidative stress. Objective: Purslane ethanolic extract effects were evaluated on antioxidant indices and sex hormone in D-gal aging female mice. Materials and Methods: 48 female NMRI mice (25-35 gr) were randomly divided into, 6 groups: 1- control (normal saline for 45 days), 2- Purslane (200 mg/kg for last 3 weeks), 3-D-gal (500 mg/kg for 45 days), 4-D-gal+Purslane, 5- Aging, 6-Aging+Purslane. Sex hormones, antioxidants and malondialdehyde (MDA) level of ovary and uterus were measured. Histological assessment was also done. Results: In D-gal treated and aging animals, LH and FSH levels were significantly increased (p |
| Databáze: | Directory of Open Access Journals |
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