A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission

Autor: Olivier Schwartz, Ferdinand Roesch, Marine Malbec
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Viruses, Vol 3, Iss 3, Pp 254-259 (2011)
Druh dokumentu: article
ISSN: 1999-4915
DOI: 10.3390/v3030254
Popis: Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only synapses and biofilms have been described for HTLV-1 transmission. Recently, Van Prooyen et al. [1] identified an additional mode of HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8.
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