| Autor: |
Alan Winston, Rebekah Puls, Stephen J Kerr, Chris Duncombe, Patrick Li, John M Gill, Reshmie Ramautarsing, Simon D Taylor-Robinson, Sean Emery, David A Cooper, ALTAIR Study Group |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 10, Iss 2, p e0118608 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0118608 |
| Popis: |
Changes in cerebral metabolite ratios (CMR) measured on 1H-MRS and changes in cognitive function (CF) are described in subjects commencing combination antiretroviral therapy (cART), although the dynamics of such changes are poorly understood.Neuroasymptomatic, HIV-infected subjects electively commencing cART were eligible. CMR were assessed in three anatomical voxels and CF assessed at baseline, week 48 and week 144. Overall differences in absolute change in CMRs and CF parameters between 0-48 and 48-144 weeks were assessed.Twenty-two subjects completed study procedures. Plasma HIV-RNA was |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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