Nasal and laryngeal sporotrichosis in an immunocompetent individual: a case report

Autor: Nabihah Roslle, Khairul Bariah Noh, Mohd Ayzam Ahmad, Ida Sadjaah Sachlin, Salina Husain
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: The Egyptian Journal of Otolaryngology, Vol 39, Iss 1, Pp 1-4 (2023)
Druh dokumentu: article
ISSN: 2090-8539
DOI: 10.1186/s43163-023-00424-0
Popis: Abstract Background Sporotrichosis is a subcutaneous mycosis caused by a dimorphic fungus, Sporothrix schenckii infection, that usually results from the traumatic implantation of the fungus into the skin and subcutaneous tissue. Disseminated cutaneous sporotrichosis is a rare entity that usually presents in the immunosuppressed individual. They are sometimes mimicking malignancy and tuberculosis. Here, a rare case of disseminated cutaneous sporotrichosis involving the larynx and nasal cavity in an immunocompetent patient is reported. Case presentation A 54-year-old healthy lady presented with hoarseness and globus sensation over the throat with prior history of multiple skin lesions over the face, limbs, and trunk. Examination revealed erythematous papular lesions over the face, limbs, and trunk. Nasoendoscopy showed sloughy mucosa over bilateral nasal cavities, nasopharynx, base of the tongue, arytenoids, and both vocal folds with bony hard mass at the left frontal recess opening. Overall imaging features were suggestive of generalized fungal infections. Multiple biopsies from multiple sites revealed Sporothrix schenckii infection. She had resolution of the lesion after being treated with intravenous Amphotericin B for a month, oral Voriconazole for another month then oral Itraconazole for 6 months. Conclusion Diagnosis of disseminated sporotrichosis can be tricky and difficult to diagnose as it can mimic other diagnoses. Education is paramount important in identifying the illness as it can be seen in immunocompetent individuals, although it is more common in the immunosuppressed individual.
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