Neisseria gonorrhea in Ethiopia, prevalence among STI suspected patients and its antimicrobial susceptibility: a systematic review and meta-analysis

Autor: Mengistie Yirsaw Gobezie, Nuhamin Alemayehu Tesfaye, Tewodros Solomon, Mulat Belete Demessie, Tesfaye Dessale Kassa, Teklehaimanot Fentie Wendie, Ermiyas Alemayehu, Minimize Hassen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Microbiology, Vol 15 (2024)
Druh dokumentu: article
ISSN: 1664-302X
49888080
DOI: 10.3389/fmicb.2024.1390001
Popis: IntroductionNeisseria gonorrhea (N. gonorrhea) represents a significant causative agent of sexually transmitted infections (STIs), posing considerable global health challenges. Despite the presence of diagnostic tools and empirically guided therapies, the escalating AMR of N. gonorrhea continues to pose a threat. This study aims to assess the prevalence of N. gonorrhea among STI suspected patients in Ethiopia and explore the patterns of AMR to common antimicrobials.MethodsFollowing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a systematic review and meta-analysis. A thorough search of electronic databases from July 11 to July 24, 2023, identified 10 eligible studies. Data were extracted and analyzed using a random-effects model. Heterogeneity was assessed using the I2 statistic, and publication bias was evaluated through Egger’s regression test and funnel plots.ResultsThe overall pooled prevalence of N. gonorrhea among STI suspected patients in Ethiopia was 20% (95% confidence interval (CI): 8–30, I2 = 99.0%; p-value
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