| Autor: |
Om P Kurmi, Lin Yang, Sanni Yaya, Zulfiqar A Bhutta, Zahid A Butt, Barthelemy Kuate Defo, Justin J Lang, Andrew T Olagunju, Jacek A Kopec, Ranjani Somayaji, Christopher J L Murray, Dilaram Acharya, Seyed-Mohammad Fereshtehnejad, Al Artaman, Ata Rafiee, Diane Lacaille, Daniel Adedayo Adeyinka, Jeffrey J Hebert, Marjan Mansourian, Thirunavukkarasu Sathish, Juwel Rana, Amin Adibi, Alice Xu, Nejat Hassen, Amani Alandejani, Sophia Sidi, Leah E Cahill, Ihoghosa Osamuyi Iyamu, Samiah Alam, Promit Ananyo Chakraborty, John Dube, Ademola Joshua Itiola, Negar Mousavi |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
RMD Open, Vol 10, Iss 1 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2056-5933 |
| DOI: |
10.1136/rmdopen-2023-003533 |
| Popis: |
Objective The objectives of this study were: (1) to describe burden of rheumatoid arthritis (RA) and trends from 1990 to 2019 using the Global Burden of Diseases, Injuries and Risk Factors Study (GBD) data, (2) to describe age and sex differences in RA and (3) to compare Canada’s RA burden to that of other countries.Methods Disease burden indicators included prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs) and disability-adjusted life-years (DALYs). GBD estimated fatal and non-fatal outcomes using published literature, survey data and health insurance claims. Data were analysed by Bayesian meta-regression, cause of death ensemble model and other statistical methods. DALYs for Canada were compared with DALYs of countries with similarly high Socio-Demographic Index values.Results In Canada, the RA prevalence rate increased by 27% between 1990 and 2019, mortality rate decreased by 27%, YLL rate decreased by 30%, YLD increased by 27% and DALY rate increased by 13%, all age standardised. The decline in RA mortality and YLL rates was especially pronounced after 2002. The disease burden was higher in females for all indicators, and DALY rates were higher among older age groups, peaking at age 75–79 years. Prevalence and DALYs were higher in Canada compared with global rates.Conclusion Trends in RA burden indicators over time and differences by age and sex have important implications for Canadian policy-makers, researchers and care providers. Early identification and management of RA in women may help reduce the overall burden of RA in Canada. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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