Acute toxicity of pyridoxine hydrochloride-containing and noncontaining antituberculosis drugs (an experimental study)
| Autor: | K. I. Usov, G. G. Yushkov, A. V. Mashanov |
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| Jazyk: | ruština |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Туберкулез и болезни лёгких, Vol 0, Iss 12, Pp 76-82 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2075-1230 2542-1506 |
| Popis: | This experimental study established DL50 (mg/kg), the degree of toxicity, and a hazard class for 17 antituberculosis drugs (OAO «Farmasintez», Irkutsk). Experiments were performed on experimental biological models: albino outbred rats (n = 3 400) and mice (n = 3 400). The incorporation of pyridoxine hydrochloride into combined antituberculosis drugs was found to considerably decrease their toxicity. |
| Databáze: | Directory of Open Access Journals |
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