Apigenin glycoside: an antioxidant isolated from Alchornea coelophylla pax & k. Hoffm. (euphorbiaceae) leaf extract
Autor: | César A Martínez, Oscar M Mosquera, Jaime Niño |
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Jazyk: | English<br />Spanish; Castilian |
Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Universitas Scientiarum, Vol 21, Iss 3, Pp 245-257 (2016) |
Druh dokumentu: | article |
ISSN: | 0122-7483 2027-1352 |
DOI: | 10.11144/Javeriana.SC21-3.agaa |
Popis: | An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was identified as Apigenin-8-C-(α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside) on the basis of spectroscopic analysis and by comparison with related values reported in the literature. This compound exhibited high in vitro antioxidant activity through DPPH• and ABTS•+ colorimetric assays with IC50 values of 7.528 and 379.7 μg. mL-1, respectively. |
Databáze: | Directory of Open Access Journals |
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