Apigenin glycoside: an antioxidant isolated from Alchornea coelophylla pax & k. Hoffm. (euphorbiaceae) leaf extract

Autor: César A Martínez, Oscar M Mosquera, Jaime Niño
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2016
Předmět:
Zdroj: Universitas Scientiarum, Vol 21, Iss 3, Pp 245-257 (2016)
Druh dokumentu: article
ISSN: 0122-7483
2027-1352
DOI: 10.11144/Javeriana.SC21-3.agaa
Popis: An antioxidant flavonoid has been isolated from methanolic leaf extract of Alchornea coelophylla Pax & K. Hoffm. by means of different column chromatography steps with DIAION HP-20 resin and silica gel in combination with analytical high-performance liquid chromatography (HPLC). It was identified as Apigenin-8-C-(α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside) on the basis of spectroscopic analysis and by comparison with related values reported in the literature. This compound exhibited high in vitro antioxidant activity through DPPH• and ABTS•+ colorimetric assays with IC50 values of 7.528 and 379.7 μg. mL-1, respectively.
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