| Autor: |
Christopher P. J. Barty, J. Martin Algots, Alexander J. Amador, James C. R. Barty, Shawn M. Betts, Marcelo A. Castañeda, Matthew M. Chu, Michael E. Daley, Ricardo A. De Luna Lopez, Derek A. Diviak, Haytham H. Effarah, Roberto Feliciano, Adan Garcia, Keith J. Grabiel, Alex S. Griffin, Frederic V. Hartemann, Leslie Heid, Yoonwoo Hwang, Gennady Imeshev, Michael Jentschel, Christopher A. Johnson, Kenneth W. Kinosian, Agnese Lagzda, Russell J. Lochrie, Michael W. May, Everardo Molina, Christopher L. Nagel, Henry J. Nagel, Kyle R. Peirce, Zachary R. Peirce, Mauricio E. Quiñonez, Ferenc Raksi, Kelanu Ranganath, Trevor Reutershan, Jimmie Salazar, Mitchell E. Schneider, Michael W. L. Seggebruch, Joy Y. Yang, Nathan H. Yeung, Collette B. Zapata, Luis E. Zapata, Eric J. Zepeda, Jingyuan Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Frontiers in Physics, Vol 12 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2296-424X |
| DOI: |
10.3389/fphy.2024.1472759 |
| Popis: |
The design and optimization of laser-Compton x-ray systems based on compact distributed charge accelerator structures can enable micron-scale imaging of disease and the concomitant production of beams of Very High Energy Electrons (VHEEs) capable of producing FLASH-relevant dose rates (∼ 10 Gy in less than 100 ns). The physics of laser-Compton x-ray scattering ensures that the x-rays produced by this process follow exactly the trajectory of the electrons from which the x-rays were produced, thus providing a route to not only compact VHEE radiotherapy but also image-guided, VHEE FLASH radiotherapy. This manuscript will review the compact accelerator architecture considerations that simultaneously optimize the production of laser-Compton x-rays from the collision of energetic laser pulses with high energy electrons and the production of high-bunch-charge VHEEs. The primary keys to this optimization are use of X-band RF accelerator structures which have been demonstrated to operate with over 100 MeV/m acceleration gradients. The operation of these structures in a distributed charge mode in which each radiofrequency (RF) cycle of the drive RF pulse is filled with a low-charge, high-brightness electron bunch is enabled by the illumination of a high-brightness photogun with a train of UV laser pulses synchronized to the frequency of the underlying accelerator system. The UV pulse trains are created by a patented pulse synthesis approach which utilizes the RF clock of the accelerator to phase and amplitude modulate a narrow band continuous wave (CW) seed laser. In this way it is possible to produce up to 10 µA of average beam current from the accelerator. Such high current from a compact accelerator enables production of sufficient x rays via laser-Compton scattering for clinical imaging and does so from a machine of “clinical” footprint. At the same time, the production of 1,000 or greater individual micro-bunches per RF pulse enables > 10 nC of charge to be produced in a macrobunch of < 100 ns. The design, construction, and test of the 100-MeV class prototype system in Irvine, CA is also presented. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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