Enzyme-secretory activity of digestive glands: non-conventional approach
| Autor: | G. F. Korotko |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 23, Iss 4, Pp 6-14 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1382-4376 2658-6673 |
| Popis: | The aim of review. To present results of original studies of the author and his collaborators, conforming to literature data on transport of digestive enzymes to blood, physiological role of this process and signal role of enzymes.Key points. Digestive glands have dual function mode. Enzymes are transported from glands to blood flow by endosecretion of glandular cells, resorption from ducts and lumen of small intestine. Exosecretions of glands have two pools of enzymes: de novo secreted and recreted from the blood. Enzymes are recreted by nondigestive glands as well. Enzymes of the gastro-intestinal tract lumen and circulating in the blood carry out hydrolytic and signal function. The latter is realized both within digestive system and outside of it. The gland ductal system takes part in adjustable endo- and exosecretory enzyme redistribution.Conclusion. Endosecreted, exosecreted and resorbed enzymes of digestive glands play role not only as accelerators of nutrient hydrolysis, but also signal molecules in modulation of alimentiry and nondigestive body functions. The ductal system of glands participates in adjustable transformations of enzyme spectrum of exosecretions. |
| Databáze: | Directory of Open Access Journals |
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