Type 2 Diabetic Patients with Ischemic Stroke: Decreased Insulin Sensitivity and Decreases in Antioxidant Enzyme Activity Are Related to Different Stroke Subtypes
| Autor: | Aleksandra Jotic, Nadezda Covickovic Sternic, Vladimir S. Kostic, Katarina Lalic, Tanja Milicic, Milija Mijajlovic, Ljiljana Lukic, Milorad Civcic, Emina Colak, Marija Macesic, Jelena P. Seferovic, Sandra Aleksic, Nebojsa M. Lalic |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | International Journal of Endocrinology, Vol 2013 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1687-8337 1687-8345 |
| DOI: | 10.1155/2013/401609 |
| Popis: | We analyzed (a) insulin sensitivity (IS) and (b) glutathione peroxidase (GSH-Px), glutathione reductase (GR), and superoxide dismutase (SOD) antioxidant enzyme activity in type 2 diabetic (T2D) patients with atherothrombotic infarction (ATI) (group A), lacunar infarction (LI) (B), or without stroke (C) and in nondiabetics with ATI (D), LI (E), or without stroke (F). ATI and LI were confirmed by brain imaging IS levels were determined by minimal model (Si index), and the enzyme activity by spectrophotometry. In T2D patients, Si was lower in A and B versus C (1.14±0.58, 1.00±0.26 versus 3.14±0.62 min−1/mU/l × 104, P |
| Databáze: | Directory of Open Access Journals |
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